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Phenotypes Associated with This Genotype
Genotype
MGI:2668440
Allelic
Composition
Grb10Gt(Betageo)1Ward/Grb10Gt(Betageo)1Ward
Genetic
Background
involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Grb10Gt(Betageo)1Ward mutation (0 available); any Grb10 mutation (38 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
embryo
• the size of the placenta was also increased ~30% relative to wild-type

growth/size/body
• neonates are ~30% larger than wild-type
• embryonic overgrowth resulting in neonates that are ~30% larger than wild-type

liver/biliary system
• disproportionate overgrowth of the liver

Mouse Models of Human Disease
OMIM ID Ref(s)
NOT Silver-Russell Syndrome; SRS 180860 J:84425


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory