Mouse Genome Informatics
hm
    Sycp3tm1Hoog/Sycp3tm1Hoog
involves: 129P2/OlaHsd * C57BL/6
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• 40% reduction in diameter
• 70% reduction in weight relative to wild-type
• spermatozoa absent from caudal epididymis
• apoptosis of meiotic spermatocytes
• arrest at zygotene stage of prophase I
• impaired chromosomal synapsis

endocrine/exocrine glands
• 40% reduction in diameter
• 70% reduction in weight relative to wild-type

Mouse Models of Human Disease
OMIM IDRef(s)
Spermatogenic Failure 4; SPGF4 270960 J:60153