Mouse Genome Informatics
hm
    Sycp3tm1Hoog/Sycp3tm1Hoog
involves: 129P2/OlaHsd * C57BL/6
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
reproductive system
• 40% reduction in diameter (J:60153)
• 70% reduction in weight relative to wild-type (J:60153)
• spermatozoa absent from caudal epididymis (J:60153)
• apoptosis of meiotic spermatocytes (J:60153)
• arrest at zygotene stage of prophase I (J:60153)
• impaired chromosomal synapsis (J:60153)
(J:60153)

endocrine/exocrine glands
• 40% reduction in diameter (J:60153)
• 70% reduction in weight relative to wild-type (J:60153)

Mouse Models of Human Disease
OMIM IDRef(s)
Spermatogenic Failure 4; SPGF4 270960 J:60153