About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:2664131
Allelic
Composition
Sycp3tm1Hoog/Sycp3tm1Hoog
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sycp3tm1Hoog mutation (0 available); any Sycp3 mutation (8 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• spermatozoa absent from caudal epididymis
• apoptosis of meiotic spermatocytes

reproductive system
• spermatozoa absent from caudal epididymis
• apoptosis of meiotic spermatocytes
• 40% reduction in diameter
• 70% reduction in weight relative to wild-type
• arrest at zygotene stage of prophase I
• impaired chromosomal synapsis

endocrine/exocrine glands
• 40% reduction in diameter
• 70% reduction in weight relative to wild-type

Mouse Models of Human Disease
OMIM ID Ref(s)
Spermatogenic Failure 4; SPGF4 270960 J:60153


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/27/2016
MGI 6.05
The Jackson Laboratory