Analysis Tools
behavior/neurological
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• one of two mutant mice tested showed diminished grip strength
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growth/size/body
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• mutants are noted as smaller than littermates
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hearing/vestibular/ear
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• hair cells of the inner ear were found to be absent upon pathological examination of two mutant mice aged 110 and 150 days; no hair cell deficiency was noted in inner ears of a 36 day old mouse
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• of four mutant mice tested for auditory brainstem response (ABR), one mouse had normal hearing, two were deaf and one exhibited reduced responses at 16 and 32 Hz
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muscle
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• degenerating muscle fibers mixed with giant fibers were observed in the spinal muscle of two mutant mice aged 110 and 150 days upon standard pathological examination
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nervous system
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• hair cells of the inner ear were found to be absent upon pathological examination of two mutant mice aged 110 and 150 days; no hair cell deficiency was noted in inner ears of a 36 day old mouse
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• the spiral ganglia of two mutant mice aged 110 and 150 days were found to be deficient in neurons upon standard pathological examination; this deficiency was not observed in a 36 day old mouse
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