Analysis Tools
renal/urinary system
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• focal hyperplasia or dysplasia is noted in 3 of 4 animals and mitotic activity in 2 of 4 animals
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• in response to nicotine, contraction in bladder strips was greatly reduced whereas contraction was easily induced in controls
(J:73590)
• contractile responses to nicotine in bladder strips from 2- to 5-day-old mutant mice are severely attenuated, despite the absence of bladder distension and
urine retention phenotype seen in Chrna3 mutant mice
(J:102601)
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