Mouse Genome Informatics
hm
    Sgcatm1Eeng/Sgcatm1Eeng
involves: 129S/SvEv * 129X1/SvJ
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
muscle
• muscle extensibility is decreased in skeletal muscle
• muscle force-generating capacity of diaphragm muscle is depressed
• mice show a loss of coupling between transverse passive stress and contractile muscle force
• skeletal muscles are stiffer in the axial, as well as in the transverse, direction to the muscle fibers

Mouse Models of Human Disease
OMIM IDRef(s)
Muscular Dystrophy, Limb-Girdle, Type 2D; LGMD2D 608099 J:83034