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Phenotypes Associated with This Genotype
Genotype
MGI:2656211
Allelic
Composition
Ceacam1tm1Bcn/Ceacam1tm1Bcn
Genetic
Background
either: (involves: 129S1/Sv * 129X1/SvJ * BALB/c) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ceacam1tm1Bcn mutation (0 available); any Ceacam1 mutation (29 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• mutants are resistant to mouse hepatitis virus A59 infection and death: they develop fewer and smaller lesions in the liver, titers of virus in the livers are 50-100-fold lower than in contrls and mutants survive a dose 100-fold higher than the lethal dose of virus for wild-type mice

immune system
• mutants are resistant to mouse hepatitis virus A59 infection and death: they develop fewer and smaller lesions in the liver, titers of virus in the livers are 50-100-fold lower than in contrls and mutants survive a dose 100-fold higher than the lethal dose of virus for wild-type mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/07/2021
MGI 6.17
The Jackson Laboratory