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Phenotypes Associated with This Genotype
Genotype
MGI:2655698
Allelic
Composition
IdeGt(OST132429)Lex/IdeGt(OST132429)Lex
Genetic
Background
involves: 129S5/SvEvBrd * C57BL/6-Tyrc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
IdeGt(OST132429)Lex mutation (2 available); any Ide mutation (68 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• accumulation of amyloid beta in the brain
• hyperglycemia 60 minutes after glucose injection
• insulin levels increased by 2.8-fold
• increased circulating insulin level

nervous system
• accumulation of amyloid beta in the brain


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory