Phenotypes for Traf2 MGI:2655569 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Traf2^tm1Mak/Traf2^tm1Mak
Genetic Background	involves: 129P2/OlaHsd * BALB/c * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Traf2^tm1Mak mutation (1 available); any Traf2 mutation (27 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:44360 )

• Background Sensitivity: on a mixed genetic background involving BALB/c, only 10% (vs expected 25%) of homozygotes are viable at 3 weeks after birth; the frequency of viable homozygotes is lower on a mixed background involving only 129 and C57BL/6 (6%), and further reduced on a background closer to the inbred B6 strain (3.4%)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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