Analysis Tools
cardiovascular system
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• 42% increase in atherosclerotic lesion area on a chow diet compared to single Apoe homozygotes at 4 months of age
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cellular
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• increased oxidative stress in serum and peritoneal and arterial macrophages
• 71% increase increase in peroxides content in arterial macrophages and 80% increase in peritoneal macrophages, decrease in glutathione content, and 19% decrease in the capacity of peritoneal macrophages to oxidize LDL
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