Phenotypes Associated with This Genotype

Genotype
MGI:2654808

• Allelic Composition: Axl^tm1Grl/Axl^tm1Grl
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

reproductive system phenotype ( J:54681 , J:133455 )

N • viable and fertile (J:54681)

N • mutant Sertoli cells exhibit normal phagocytosis of apoptotic spermatogenic cells relative to wild-type controls, as determined by lipid droplet formation using Oil Red O staining (J:133455)

cardiovascular system

increased vascular permeability ( J:198769 )

• in the liver

mortality/aging

mortality/aging ( J:54681 )

N • homozygotes are viable and fertile