endocrine/exocrine glands
small testis
(
J:54681
)
|
|
reproductive system
small testis
(
J:54681
)
|
|
|
• 3.7% of females exhibit vaginal atresia
|
|
• reduced amount of mature sperm in the epididymis
|
|
• double mutant Sertoli cells show a ~35% decrease in phagocytosis of apoptotic spermatogenic cells relative to wild-type controls, as determined by lipid droplet formation using Oil Red O staining; this reduction is similar to that observed in Mertktm1Grl singly mutant Sertoli cells
|
cellular
|
• reduced amount of mature sperm in the epididymis
|