Phenotypes Associated with This Genotype

Genotype
MGI:2654779

• Allelic Composition: Tyro3^tm1Grl/Tyro3^tm1Grl
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal seizure response to inducing agent ( J:54681 )

• activity-induced seizures are observed in mutants more than 7 months old

nervous system

abnormal seizure response to inducing agent ( J:54681 )

• activity-induced seizures are observed in mutants more than 7 months old

vision/eye

vision/eye phenotype ( J:116526 )

N • retinas appear normal with no photoreceptor degeneration

reproductive system

reproductive system phenotype ( J:133455 )

N • mutant Sertoli cells exhibit normal phagocytosis of apoptotic spermatogenic cells relative to wild-type controls, as determined by lipid droplet formation using Oil Red O staining

cardiovascular system

cardiovascular system phenotype ( J:198769 )

N • mice exhibit normal vascular permeability in the liver