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Phenotypes Associated with This Genotype
Genotype
MGI:2654625
Allelic
Composition		 Pax5tm1Mbu/Pax5+
Genetic
Background		 involves: 129S2/SvPas * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pax5tm1Mbu mutation (1 available); any Pax5 mutation (40 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal cerebellum morphology ( J:113076 )
• culmen of cerebellum is slightly expanded anteriorly, but inferior colliculus appears normal as opposed to homozygotes
abnormal cerebellar lobule formation ( J:113076 )
• only shallow intraculminate fissure is observed compared to homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory