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Phenotypes Associated with This Genotype
Genotype
MGI:2653622
Allelic
Composition
Cdkn1btm1Mlf/Cdkn1btm1Mlf
Tg(MMTV-vHaras)SH1Led/0
Genetic
Background
involves: 129S4/SvJaeSor * C57BL/6J * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdkn1btm1Mlf mutation (2 available); any Cdkn1b mutation (26 available)
Tg(MMTV-vHaras)SH1Led mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
neoplasm
• mice exhibit no effect on the timing or multiplicity of tumor formation, which is largely restricted to mammary and salivary glands, however, once tumors appear, they grow faster than in controls
• the increase in growth rate of induced tumors is particularly striking for salivary tumors


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory