Phenotypes Associated with This Genotype

Genotype
MGI:2653210

• Allelic Composition: Zic2^tm1Jaru/Zic2⁺
• Genetic Background: B6.129S4-Zic2^tm1Jaru

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:72342 )

N • mutants exhibit normal spontaneous locomotor activity, motor coordination ability, neuromuscular strength, motivation and emotional behavior

increased startle reflex ( J:72342 )

• acoustic startle response is larger, with an amplitude twice that of wild-type

nervous system

decreased prepulse inhibition ( J:72342 )

• the prepulse inhibition level is attenuated both with the 70-dB and 80-dB prepulses