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Phenotypes Associated with This Genotype
Genotype
MGI:2652121
Allelic
Composition
Fyntm1Sor/Fyn+
Tg(Camk2a-Fyn-531)1Nko/0
Genetic
Background
involves: 129S7/SvEvBrd * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fyntm1Sor mutation (3 available); any Fyn mutation (37 available)
Tg(Camk2a-Fyn-531)1Nko mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• sudden death after weaning; survival rate shows correlation with level of transgene expression

behavior/neurological
• lines expressing high levels of the transgene show spontaneous running and bouncing fits
• tonic convulsion

nervous system
• tonic convulsion


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory