Analysis Tools
mortality/aging
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• pups die within 1 day after birth
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craniofacial
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• incisors are smaller in diameter and exhibit abnormal folding of the inner dental epithelium
• incisors show an absence of the papillary layer
|
|
• first and second molars of both the maxilla and mandible are abnormally fused, forming a single gigantic anlage
• dental cord is virtually absent
• the stellate reticulum is hypocellular and shows absence of early vascular loops in the coronal aspect
• the outer dental epithelium forms a continuous layer without the gaps seen in controls
|
|
• cusps of first molars are shallow, broad, underdeveloped and misshapen
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fused molars
(
J:80081
)
|
• first and second molars of both the maxilla and mandible are abnormally fused, forming a single gigantic anlage
|
|
• exhibit abnonormally short ameloblasts in the most advanced cusps of first molar region that are overlaid by a scarce, squamous stratum intermedium
• in incisors, the cuboidal ameloblasts are only 15% of the apical-basal height and contain centrally located round nuclei
• mitochondria, RER, and Golgi are sparse and evenly distributed in the cytoplasm of incisor ameloblasts and Tomes' processes and the terminal webs do not develop
• amelolasts exhibit premature withdrawal from the cell cylce
|
|
• Tomes' processes do not develop
|
|
• the epithelial enamel organ appears disorganized at the late bell stage in the principal cusps of the first molars
|
|
• in molars, the stellate reticulum is hypocellular and shows absence of early vascular loops in the coronal aspect
|
|
• incisors exhibit abnormal folding of the inner dental epithelium
|
|
• in molars, the outer dental epithelium forms a continuous layer without the gaps observed in controls
|
|
• molars develop close to the oral surface, indicating virtual absence of a dental cord
|
growth/size/body
|
• incisors are smaller in diameter and exhibit abnormal folding of the inner dental epithelium
• incisors show an absence of the papillary layer
|
|
• first and second molars of both the maxilla and mandible are abnormally fused, forming a single gigantic anlage
• dental cord is virtually absent
• the stellate reticulum is hypocellular and shows absence of early vascular loops in the coronal aspect
• the outer dental epithelium forms a continuous layer without the gaps seen in controls
|
|
• cusps of first molars are shallow, broad, underdeveloped and misshapen
|
fused molars
(
J:80081
)
|
• first and second molars of both the maxilla and mandible are abnormally fused, forming a single gigantic anlage
|
|
• exhibit abnonormally short ameloblasts in the most advanced cusps of first molar region that are overlaid by a scarce, squamous stratum intermedium
• in incisors, the cuboidal ameloblasts are only 15% of the apical-basal height and contain centrally located round nuclei
• mitochondria, RER, and Golgi are sparse and evenly distributed in the cytoplasm of incisor ameloblasts and Tomes' processes and the terminal webs do not develop
• amelolasts exhibit premature withdrawal from the cell cylce
|
|
• Tomes' processes do not develop
|
|
• the epithelial enamel organ appears disorganized at the late bell stage in the principal cusps of the first molars
|
|
• in molars, the stellate reticulum is hypocellular and shows absence of early vascular loops in the coronal aspect
|
|
• incisors exhibit abnormal folding of the inner dental epithelium
|
|
• in molars, the outer dental epithelium forms a continuous layer without the gaps observed in controls
|
|
• molars develop close to the oral surface, indicating virtual absence of a dental cord
|
skeleton
|
• incisors are smaller in diameter and exhibit abnormal folding of the inner dental epithelium
• incisors show an absence of the papillary layer
|
|
• first and second molars of both the maxilla and mandible are abnormally fused, forming a single gigantic anlage
• dental cord is virtually absent
• the stellate reticulum is hypocellular and shows absence of early vascular loops in the coronal aspect
• the outer dental epithelium forms a continuous layer without the gaps seen in controls
|
|
• cusps of first molars are shallow, broad, underdeveloped and misshapen
|
fused molars
(
J:80081
)
|
• first and second molars of both the maxilla and mandible are abnormally fused, forming a single gigantic anlage
|
|
• exhibit abnonormally short ameloblasts in the most advanced cusps of first molar region that are overlaid by a scarce, squamous stratum intermedium
• in incisors, the cuboidal ameloblasts are only 15% of the apical-basal height and contain centrally located round nuclei
• mitochondria, RER, and Golgi are sparse and evenly distributed in the cytoplasm of incisor ameloblasts and Tomes' processes and the terminal webs do not develop
• amelolasts exhibit premature withdrawal from the cell cylce
|
|
• Tomes' processes do not develop
|
|
• the epithelial enamel organ appears disorganized at the late bell stage in the principal cusps of the first molars
|
|
• in molars, the stellate reticulum is hypocellular and shows absence of early vascular loops in the coronal aspect
|
|
• incisors exhibit abnormal folding of the inner dental epithelium
|
|
• in molars, the outer dental epithelium forms a continuous layer without the gaps observed in controls
|
|
• molars develop close to the oral surface, indicating virtual absence of a dental cord
|
