Phenotypes for Pde4d MGI:2451222 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Pde4d^tm1Mct/Pde4d^tm1Mct
Genetic Background	involves: 129P2/OlaHsd * 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pde4d^tm1Mct mutation (3 available); any Pde4d mutation (184 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:58116 )

• Background Sensitivity: exacerbated on the 129X1/SvJ background compared to mixed 129P2/OlaHsd and C57BL/6 background; only 9.5% of homozygous null mice are recovered at D30

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/06/2026 MGI 6.24