Phenotypes for Met MGI:2450977 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Met^tm1Cpo/Met^tm2Cpo
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Met^tm1Cpo mutation (0 available); any Met mutation (81 available)
Met^tm2Cpo mutation (0 available); any Met mutation (81 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:36244 )

• animals die within a few minutes after birth due to respiratory failure

• animals display curled fetal position

muscle

decreased skeletal muscle mass ( J:36244 )

• reduced total muscle mass

respiratory system

respiratory failure ( J:36244 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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