Phenotypes Associated with This Genotype

Genotype
MGI:2450698

• Allelic Composition: Tg(LIPG)1Tq/0
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

decreased circulating cholesterol level ( J:81821 )

• male animals show 17% decrease in total cholesterol levels

decreased circulating HDL cholesterol level ( J:81821 )

• male animals show 19% decrease in HDL cholesterol levels

abnormal circulating phospholipid level ( J:81821 )

• female animals show 19% decrease in serum phospholipid levels

• male animals show 21% decrease in serum phospholipid levels

• 26% decrease in apoA1 levels

decreased triglyceride level ( J:81821 )

• male animals show decreased triglyceride levels

cardiovascular system

abnormal vascular endothelial cell physiology ( J:95158 )

• isolated aortic strips exhibit a 68% increased monocyte binding compared to wild-type strips