Mouse Genome Informatics
hm
    Hbatm1Paz/Hbatm1Paz
involves: 129S7/SvEvBrd
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• death between E14.5 and E16.5: all homozygotes are dead by E16.5

growth/size/body
• noticeably smaller than littermates at E14.5

hematopoietic system
• presence of large inclusion bodies in red blood cells at E14.5
• decreased mean cell hemoglobin content

homeostasis/metabolism
• hydrops fetalis

Mouse Models of Human Disease
OMIM IDRef(s)
Hemoglobin--Alpha Locus 1; HBA1 141800 J:28392
Hydrops Fetalis, Nonimmune; NIHF 236750 J:28392