Phenotypes Associated with This Genotype

Genotype
MGI:2450534

• Allelic Composition: Hba^tm1Paz/Hba^tm1Paz
• Genetic Background: involves: 129S7/SvEvBrd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

lethality throughout fetal growth and development, complete penetrance ( J:28392 )

• death between E14.5 and E16.5: all homozygotes are dead by E16.5

growth/size/body

decreased fetal size ( J:28392 )

• noticeably smaller than littermates at E14.5

hematopoietic system

abnormal erythrocyte morphology ( J:28392 )

• presence of large inclusion bodies in red blood cells at E14.5

decreased mean corpuscular hemoglobin ( J:28392 )

• decreased mean cell hemoglobin content

decreased mean corpuscular volume ( J:28392 )

homeostasis/metabolism

hydrops fetalis ( J:28392 )

• hydrops fetalis