Analysis Tools
endocrine/exocrine glands
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• testes of adult mutant males were significantly lower in weight as compared to heterozygous and wild-type controls
• epididymal and seminal vesicle weights were comparable to controls
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reproductive system
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• testes of adult mutant males were significantly lower in weight as compared to heterozygous and wild-type controls
• epididymal and seminal vesicle weights were comparable to controls
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• most seminiferous tubules contained pachytene spermatocytes with condensed nuclei, some of which appeared fragmented and apoptotic
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• mice were deficient in postmeiotic spermatids and lacked spermatozoa in the epididymis
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