Mouse Genome Informatics
hm
    Fcgr2btm1Ttk/Fcgr2btm1Ttk
C.129S4-Fcgr2btm1Ttk
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
N
• mice have life spans comparable to wild-type littermates (J:64152)

immune system
• mice infected with Plasmodium chabaudi chabaudi exhibit lower peak levels of parasitemia and quicker resolution, less severe anemia, less severe hypothermia, increased phagocytosis of malarial parasites by macrophages, increased TNF-alpha production from macrophages ingesting malaria parasite and increased anti-malarial antibody titers compared with wild-type mice

Mouse Models of Human Disease
OMIM IDRef(s)
Malaria, Susceptibility to 611162 J:120905