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Phenotypes Associated with This Genotype
Genotype
MGI:2447466
Allelic
Composition
Cx3cl1tm1Lira/Cx3cl1tm1Lira
Genetic
Background
involves: 129S/SvEv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cx3cl1tm1Lira mutation (0 available); any Cx3cl1 mutation (7 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• mice do not exhibit overt behavioral abnormalities

immune system
N
• the lymph node cellular composition does not differ significantly from that of control mice
• the responses of mutant mice to a variety of inflammatory stimuli, including thioglycolate, L. monocytogenes, KLH and DSS, are indistinguishable from those of control mice

nervous system
N
• histological analysis of their brains and many other tissues did not reveal any gross changes compared to controls

hematopoietic system
N
• mice have normal hematological profiles, including red blood cell number and hematocrit, except for a decrease in the number of blood leukocytes expressing the cell surface marker F4/80


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory