Phenotypes Associated with This Genotype

Genotype
MGI:2447466

• Allelic Composition: Cx3cl1^tm1Lira/Cx3cl1^tm1Lira
• Genetic Background: involves: 129S/SvEv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:68831 )

N • mice do not exhibit overt behavioral abnormalities

immune system

immune system phenotype ( J:68831 )

N • the lymph node cellular composition does not differ significantly from that of control mice

N • the responses of mutant mice to a variety of inflammatory stimuli, including thioglycolate, L. monocytogenes, KLH and DSS, are indistinguishable from those of control mice

nervous system

nervous system phenotype ( J:68831 )

N • histological analysis of their brains and many other tissues did not reveal any gross changes compared to controls

hematopoietic system

hematopoietic system phenotype ( J:68831 )

N • mice have normal hematological profiles, including red blood cell number and hematocrit, except for a decrease in the number of blood leukocytes expressing the cell surface marker F4/80