Phenotypes Associated with This Genotype

Genotype
MGI:2388134

• Allelic Composition: Rxfp2^tm1Aia/Rxfp2^tm1Aia
• Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

azoospermia ( J:79124 )

♂ • absence of spermatids and mature sperm

reproductive system

azoospermia ( J:79124 )

♂ • absence of spermatids and mature sperm

small testis ( J:79124 )

♂

bilateral cryptorchism ( J:79124 )

♂ • bilaterally undescended testis located in the high intraabdominal position

arrest of spermatogenesis ( J:79124 )

♂

abnormal gubernaculum morphology ( J:79124 )

• extended gubernaculum

abnormal inguinal canal morphology ( J:79124 )

• inguinal canal fails to form

male infertility ( J:79124 )

♂

endocrine/exocrine glands

small testis ( J:79124 )

♂

bilateral cryptorchism ( J:79124 )

♂ • bilaterally undescended testis located in the high intraabdominal position

skeleton

abnormal gubernaculum morphology ( J:79124 )

• extended gubernaculum

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cryptorchidism		DOID:11383	OMIM:219050	J:79124