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Phenotypes Associated with This Genotype
Genotype
MGI:2385623
Allelic
Composition		 Tg(APOB)11Rub/?
Genetic
Background		 involves: FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
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♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
increased circulating cholesterol level ( J:78212 )
• non-HDL plasma levels are increased (98 mg/dl compared to 23 mg/dl in wild-type mice)
increased circulating LDL cholesterol level ( J:78212 )
• plasma LDL is increased greater than 4-fold compared to in wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory