Phenotypes Associated with This Genotype

Genotype
MGI:2183364

• Allelic Composition: Msh2^tm1Mak/Msh2^tm1Mak
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:28397 )

• between 2 and 5 months of age, due to tumor-related illness

neoplasm

increased lymphoma incidence ( J:28397 )

• increased incidence of metastasizing lymphoma, beginning ~2 months of age, incomplete penetrance

immune system

immune system phenotype ( J:28397 )

N • no gross abnormalities were seen