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Phenotypes Associated with This Genotype
Genotype
MGI:2183195
Allelic
Composition
Mdm2tm1Bay/Mdm2tm1Bay
Trp53tm1Brd/Trp53tm1Brd
Genetic
Background
involves: 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mdm2tm1Bay mutation (1 available); any Mdm2 mutation (54 available)
Trp53tm1Brd mutation (5 available); any Trp53 mutation (232 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• mice are normal, fertile and indistinguishable from controls, suggesting that the absence of Trp53 resuces the embryonic lethal phenotype of the Mdm2tm1Bay homozygous mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory