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Phenotypes Associated with This Genotype
Genotype
MGI:2183195
Allelic
Composition		 Mdm2tm1Bay/Mdm2tm1Bay
Trp53tm1Brd/Trp53tm1Brd
Genetic
Background		 involves: 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mdm2tm1Bay mutation (1 available); any Mdm2 mutation (51 available)
Trp53tm1Brd mutation (5 available); any Trp53 mutation (237 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:29811 )
• mice are normal, fertile and indistinguishable from controls, suggesting that the absence of Trp53 resuces the embryonic lethal phenotype of the Mdm2tm1Bay homozygous mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory