Phenotypes Associated with This Genotype

Genotype
MGI:2181575

• Allelic Composition: Fgfr1^tm1Jrt/Fgfr1^tm6.1Jrt
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

abnormal axial skeleton morphology ( J:49154 )

rib fusion ( J:49154 )

• rib (27%) fusion occurs in newborn mice

abnormal vertebrae morphology ( J:49154 )

• vertebral transformations to posterior direction

• however, the number of caudal vertebrae is not reduced

thoracic vertebral transformation ( J:49154 )

• transformations of T1 to T2 (11%), T12 to L1 (44%), and T13 to L1 (11%)

cervical vertebral transformation ( J:49154 )

• transformations of C5 to C6 (22%), C6 to C7 (11%), and C7 to T1 (44%)

lumbar vertebral transformation ( J:49154 )

• transformations of L5 to S1 (11%) and L6 to S1 (55%)

sacral vertebral transformation ( J:49154 )

• transformations of S1 to S2 (44%) and S3 to S4 (28%)