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Phenotypes Associated with This Genotype
Genotype
MGI:2181514
Allelic
Composition		 Juntm1Pa/Juntm1Pa
Genetic
Background		 either: (involves: 129S/SvEv * 129X1/SvJ) or (involves: 129X1/SvJ * C57BL/6J)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Juntm1Pa mutation (1 available); any Jun mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality during organogenesis, complete penetrance ( J:13175 )
• die at mid-gestation, with the majority dying between E11.5 and E13.5

cellular
decreased fibroblast proliferation ( J:13175 )
• primary fibroblasts show greatly reduced growth rates in culture, even in the presence of various mitogens

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory