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Phenotypes Associated with This Genotype
Genotype
MGI:2180833
Allelic
Composition
Zic3tm1Bca/Zic3tm1Bca
Genetic
Background
involves: 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zic3tm1Bca mutation (0 available); any Zic3 mutation (37 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• despite normal numbers at E9.5, fewer than expected mice at E15.5 and weaning

cardiovascular system
• interruption with separate entrance of hepatic veins in some mice
• in 4 of 18 mice at E9.5
• sinisteral looping in some mice
• in some mice
• atrium isomerism in some mice
• in some mice

digestive/alimentary system
• in 5 of 58 mice at E15.5
• midline and right-sided stomach in some mice
• in some mice

embryo
• in 12 of 18 mice
• in 5 of 58 mice at E15.5
• in some mice at E9.5

growth/size/body
• in 12 of 18 mice
• in some mice at E9.5
• in 5 of 58 mice at E15.5
• laterality defects in 3 of 15 mice
• in some mice
• in some mice

craniofacial
• in 5 of 58 mice at E15.5

nervous system
• in 5 of 58 mice at E15.5
• in some mice at E9.5
• in 5 of 58 mice at E15.5

respiratory system
• pulmonary isomerism in some mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory