Mouse Genome Informatics
hm
    Lamb3IAP/Lamb3IAP
involves: C3H * C57BL/6
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       

Control and Lamb3IAP/Lamb3IAP histological skin section.

mortality/aging
• animals died within 24 hours of birth, usually without feeding

respiratory system
• epithelial layer delaminated in nasopharynx
• epithelial layer delaminated in oropharynx

digestive/alimentary system
• epithelial layer delaminated

craniofacial
• epithelial layer delaminated

integument
• the entire epithelial layer often delaminated from the distal limbs
• clear fluid blisters appear at frictional areas

growth/size
• epithelial layer delaminated

Mouse Models of Human Disease
OMIM IDRef(s)
Epidermolysis Bullosa, Junctional, Herlitz Type 226700 J:42382
Epidermolysis Bullosa, Junctional, Non-Herlitz Type 226650 J:42382