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Phenotypes Associated with This Genotype
Genotype
MGI:2178746
Allelic
Composition		 Hoxd10tm1Mrc/Hoxd10+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxd10tm1Mrc mutation (0 available); any Hoxd10 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal stationary movement ( J:44765 )
• inability to bring hindlegs towards the ventral midline
abnormal gait ( J:44765 )
• incomplete penetrance and variable severity

skeleton
abnormal vertebral transverse process morphology ( J:44765 )
• unilateral fusions of four transverse processes, incomplete penetrance

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/31/2026
MGI 6.24 		The Jackson Laboratory