Phenotypes for Hoxa11 Hoxd MGI:2178140 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Hoxa11^tm1Ssp/Hoxa11^tm1Ssp Hoxd^tm3Ddu/Hoxd^tm3Ddu
Genetic Background	involves: 129S2/SvPas * C57BL/6 * CF-1 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxa11^tm1Ssp mutation (0 available); any Hoxa11 mutation (10 available)
Hoxd^tm3Ddu mutation (0 available); any Hoxd mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

increased diameter of radius ( J:47900 )

• thickening of radius

increased diameter of ulna ( J:47900 )

• thickening of ulna

abnormal fibula morphology ( J:47900 )

• lack of distal fusion of tibia and fibula

increased diameter of fibula ( J:47900 )

• thickening of fibula

abnormal tibia morphology ( J:47900 )

• lack of distal fusion of tibia and fibula

increased diameter of tibia ( J:47900 )

• thickening of tibia

skeleton

increased diameter of radius ( J:47900 )

• thickening of radius

increased diameter of ulna ( J:47900 )

• thickening of ulna

abnormal fibula morphology ( J:47900 )

• lack of distal fusion of tibia and fibula

increased diameter of fibula ( J:47900 )

• thickening of fibula

abnormal tibia morphology ( J:47900 )

• lack of distal fusion of tibia and fibula

increased diameter of tibia ( J:47900 )

• thickening of tibia

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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