Analysis Tools
cellular
 |
• 75% reduction of epididymal sperm count relative to wild-type
|
|
|
• 40% reduction in the number of motile sperm relative to wild-type
|
endocrine/exocrine glands
 |
• blocked prior to antral follicle formation
|
small ovary
(
J:38099
)
|
|
|
small testis
(
J:38099
)
|
|
• progressive reduction in size beginning at 14 days of age
• however, serum testosterone levels in males were similar to those of wild-type
and the epididymides and seminal glands were of normal size
|
homeostasis/metabolism
|
• elevated only in females
|
|
• 50% decrease relative to wild-type
|
|
• FSH was undetected in the pituitary
|
|
• FSH was undetected in serum
|
reproductive system
|
|
• 75% reduction of epididymal sperm count relative to wild-type
|
|
|
• 40% reduction in the number of motile sperm relative to wild-type
|
|
|
• blocked prior to antral follicle formation
|
small ovary
(
J:38099
)
|
|
|
small testis
(
J:38099
)
|
|
• progressive reduction in size beginning at 14 days of age
• however, serum testosterone levels in males were similar to those of wild-type
and the epididymides and seminal glands were of normal size
|
small uterus
(
J:38099
)
|
|
• markedly thinner than wild-type
|
|
|
• females but not males are infertile
|
