Mouse Genome Informatics
hm
    Hexatm1Rlp/Hexatm1Rlp
involves: 129S4/SvJae * C57BL/6
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
nervous system
• accumulation of GM2 gangliosides levels reach 15% of total gangliosides
• levels reach 15% of total gangliosides
• number of storage neurons with membranous cytoplasmic bodies increases with age
• distribution of storage neurons found in cerebral cortex, piriform and entorhinal cortices, CA3, amygdala, mammillary bodies, septal nuclei, and nuclei in the hypothalamus

Mouse Models of Human Disease
OMIM IDRef(s)
Tay-Sachs Disease; TSD 272800 J:21008