Phenotypes Associated with This Genotype

Genotype
MGI:2177169

• Allelic Composition: Foxa2^tm1Jrt/Foxa2⁺
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:19895 )

• about 20% of those that survive until weaning die by 3 months of age and display abnormalities

postnatal lethality ( J:19895 )

• Background Sensitivity: loss prior to weaning is higher on a mixed 129 and C57BL/6 background than on a 129 background or mixed 129 and CD-1 background

craniofacial

long incisors ( J:19895 )

• overgrowth of the upper and lower incisors is seen in mice with malocclusion

malocclusion ( J:19895 )

• malocclusion of the jaws is seen in those that die by 3 months of age

behavior/neurological

hunched posture ( J:19895 )

• seen in those that die by 3 months of age

circling ( J:19895 )

• seen in those that die by 3 months of age

growth/size/body

long incisors ( J:19895 )

• overgrowth of the upper and lower incisors is seen in mice with malocclusion

malocclusion ( J:19895 )

• malocclusion of the jaws is seen in those that die by 3 months of age

decreased body size ( J:19895 )

• seen in those that die by 3 months of age

skeleton

long incisors ( J:19895 )

• overgrowth of the upper and lower incisors is seen in mice with malocclusion

malocclusion ( J:19895 )

• malocclusion of the jaws is seen in those that die by 3 months of age