Phenotypes for Aplp2 App MGI:2176994 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Aplp2^tm1Dbo/Aplp2^tm1Dbo App^tm2Cwe/App^tm2Cwe
Genetic Background	involves: 129/Sv * 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aplp2^tm1Dbo mutation (1 available); any Aplp2 mutation (30 available)
App^tm2Cwe mutation (0 available); any App mutation (89 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:65196 )

• no defect detected grossly or microscopically

• no animals survive to weaning age

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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