Mouse Genome Informatics
hm
    Gcktm1Ts/Gcktm1Ts
either: (involves: 129S7/SvEvBrd * C57BL/6J) or (involves: 129S7/SvEvBrd * DBA/2J)
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• death between postnatal days 3 and 5 (P3 - P5)
• cessation of feeding postnatal day 3 (P3)

liver/biliary system
• microvesicular steatosis (vacuolization and lipid accumulation)

homeostasis/metabolism
• increased serum concentration of cholesterol
• increased serum concentrations of triglycerides
• reduction in glycogen stores

Mouse Models of Human Disease
OMIM IDRef(s)
Maturity-Onset Diabetes of the Young, Type 2; MODY2 125851 J:29255