Mouse Genome Informatics
cn
    Brca1tm1Cxd/Brca1tm2Cxd
Trp53tm1Brd/Trp53+
Tg(MMTV-cre)4Mam/0

involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
tumorigenesis
• by 6-8 months of age, 8 of 11 females developed mammary gland tumors that exhibited several distinct histopathologies

Mouse Models of Human Disease
OMIM IDRef(s)
Breast Cancer 114480 J:54533
Breast-Ovarian Cancer, Familial, Susceptibility to, 1; BROVCA1 604370 J:54533