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Phenotypes Associated with This Genotype
Genotype
MGI:2176776
Allelic
Composition
Grm7tm1Nak/Grm7tm1Nak
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Grm7tm1Nak mutation (0 available); any Grm7 mutation (124 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mice do not exhibit taste aversion behavior following conditioning with lithium chloride injection
• however, taste preferences and sensitivity to lithium chloride are normal
• mice exhibit reduced freezing compared to wild-type mice in response to a fear stimuli
• however, pain sensitivity and motor processing capacities are normal
• mice older than 12 weeks exhibit epilepsy, particularly when placed into a new chamber

nervous system
• mice older than 12 weeks exhibit epilepsy, particularly when placed into a new chamber


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory