Analysis Tools
vision/eye
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• electroretinogram shows that the b-wave is fully abolished under both dark- or light-adapted conditions, indicating impaired synaptic transmission in ON bipolar cells, however retinal organization and projection of optic fibers to the brain are normal
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nervous system
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• impairment of synaptic transmission in ON bipolar cells of the retina and absent ON response, but not OFF response, in the superior colliculus
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behavior/neurological
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• no difference in avoidance learning acqusition in response to light exposure between wild-type and mutants
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