Phenotypes Associated with This Genotype

Genotype
MGI:2175173

• Allelic Composition: Nrgn^tm1Kph/Nrgn^tm1Kph
• Genetic Background: involves: 129/Sv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

impaired synaptic plasticity ( J:65166 )

• mice exhibit impaired short term plasticity and altered induction

abnormal long-term potentiation ( J:65166 )

• mice exhibit impaired long term potentiation (LTP) in the CA1 region and altered induction of LTP

behavior/neurological

abnormal spatial learning ( J:65166 )

• spatial learning impairment in Morris water maze test