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Phenotypes Associated with This Genotype
Genotype
MGI:2174969
Allelic
Composition
Mapttm1Noh/Mapttm1Noh
Genetic
Background
involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mapttm1Noh mutation (0 available); any Mapt mutation (408 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• abnormal cerebellar parallel fiber axons; reduction in microtubule (MT) number and density and reduction in frequency of cross-bridges between MTs
• mice exhibit no other obvious abnormalities

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
NOT Alzheimer's disease DOID:10652 OMIM:104300
OMIM:502500
OMIM:604154
OMIM:608907
J:19030


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/12/2017
MGI 6.10
The Jackson Laboratory