Phenotypes associated with this allele

• Allele Symbol: Tyk2^{tm2b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 2b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:6120762
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tyk2^tm2b(EUCOMM)Hmgu/Tyk2^tm2b(EUCOMM)Hmgu	C57BL/6N-Tyk2^tm2b(EUCOMM)Hmgu/Ieg	MGI:6263803

Genotype
MGI:6263803

hm1

• Allelic Composition: Tyk2^{tm2b(EUCOMM)Hmgu}/Tyk2^{tm2b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Tyk2^{tm2b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0809_8_G11

Data Sources

IMPC Data for Tyk2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

enlarged thymus ( J:211773 )

♂

IMPC - HMGU

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - HMGU

abnormal pancreas morphology ( J:211773 )

♂

IMPC - HMGU

abnormal ovary morphology ( J:211773 )

♀

IMPC - HMGU

growth/size/body

enlarged spleen ( J:211773 )

♂

IMPC - HMGU

hematopoietic system

enlarged thymus ( J:211773 )

♂

IMPC - HMGU

enlarged spleen ( J:211773 )

♂

IMPC - HMGU

thrombocytopenia ( J:211773 )

♂

IMPC - HMGU

decreased plasmacytoid dendritic cell number ( J:211773 )

IMPC - HMGU

immune system

enlarged thymus ( J:211773 )

♂

IMPC - HMGU

enlarged spleen ( J:211773 )

♂

IMPC - HMGU

decreased plasmacytoid dendritic cell number ( J:211773 )

IMPC - HMGU

limbs/digits/tail

long tibia ( J:211773 )

♀

IMPC - HMGU

reproductive system

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - HMGU

abnormal ovary morphology ( J:211773 )

♀

IMPC - HMGU

skeleton

long tibia ( J:211773 )

♀

IMPC - HMGU