Phenotypes associated with this allele

• Allele Symbol: Gsdmd^em1Flv
• Allele Name: endonuclease-mediated mutation 1, Richard Flavell
• Allele ID: MGI:5910442
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gsdmd^em1Flv/Gsdmd^em1Flv	C57BL/6N-Gsdmd^em1Flv	MGI:6106895

Genotype
MGI:6106895

hm1

• Allelic Composition: Gsdmd^em1Flv/Gsdmd^em1Flv
• Genetic Background: C57BL/6N-Gsdmd^em1Flv

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

digestive/alimentary system

diarrhea ( J:243487 )

• increased occurrence after oral rotavirus inoculation of 8 day old pups

immune system

increased susceptibility to Riboviria infection induced morbidity/mortality ( J:243487 )

• increased sensitivity to and pathology of oral rotavirus inoculation of 8 day old pups

• elevated viral load in ileum after oral rotavirus inoculation of 8 day old pups

mortality/aging

increased susceptibility to Riboviria infection induced morbidity/mortality ( J:243487 )

• increased sensitivity to and pathology of oral rotavirus inoculation of 8 day old pups

• elevated viral load in ileum after oral rotavirus inoculation of 8 day old pups