Phenotypes associated with this allele

• Allele Symbol: Ltbp3^blfc
• Allele Name: blunt face
• Allele ID: MGI:5816840
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ltbp3^blfc/Ltbp3^blfc	LT.Cg-Ltbp3^blfc/J	MGI:5819093

Genotype
MGI:5819093

hm1

• Allelic Composition: Ltbp3^blfc/Ltbp3^blfc
• Genetic Background: LT.Cg-Ltbp3^blfc/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

round orbits ( J:238326 )

• orbits are round not oblong

short face ( J:238326 )

• homozygotes have a shortened face with blunted nose and wide-set eyes

abnormal nose morphology ( J:238326 )

• blunted nose

skeleton

round orbits ( J:238326 )

• orbits are round not oblong

vision/eye

abnormal eye morphology ( J:238326 )

• corneal holes were found in each of two homozygous males at 2 months of age and a corneal hole in one eye and iris coloboma with optic cup ring in the other eye were found in one homozygous female at 2 months of age

round orbits ( J:238326 )

• orbits are round not oblong

iris coloboma ( J:238326 )

ocular hypertelorism ( J:238326 )

• wide-set eyes

mortality/aging

preweaning lethality, incomplete penetrance ( J:238326 )

• some homozygotes die before wean age

respiratory system

abnormal nose morphology ( J:238326 )

• blunted nose

growth/size/body

short face ( J:238326 )

• homozygotes have a shortened face with blunted nose and wide-set eyes

abnormal nose morphology ( J:238326 )

• blunted nose

decreased body size ( J:238326 )

• some homozygotes are scarcely half the normal size at 2 weeks of age, and mature body size remains only two-thirds to three-quarters normal size