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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(tetO-DRD3)3-10Kndl
transgene insertion 3-10, Eric R Kandel
MGI:5693547
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-DRD3)3-10Kndl/0 		involves: C57BL/6 * CBA MGI:5694057


Genotype
MGI:5694057
cx1
Allelic
Composition		 Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-DRD3)3-10Kndl/0
Genetic
Background		 involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Camk2a-tTA)1Mmay mutation (8 available)
Tg(tetO-DRD3)3-10Kndl mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal emotion/affect behavior ( J:225565 )
• reduced number of total lever presses in progressive ratio (PR) measure of incentive motivation
• mice exhibit less motivation to obtain food reward




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory