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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Denrtm1b(KOMP)Wtsi
targeted mutation 1b, Wellcome Trust Sanger Institute
MGI:5637029
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Denrtm1b(KOMP)Wtsi/Denrtm1b(KOMP)Wtsi C57BL/6N-Denrtm1b(KOMP)Wtsi/Wtsi MGI:5767629
ht2
Denrtm1b(KOMP)Wtsi/Denr+ C57BL/6N-Denrtm1b(KOMP)Wtsi/Wtsi MGI:5797474


Genotype
MGI:5767629
hm1
Allelic
Composition
Denrtm1b(KOMP)Wtsi/Denrtm1b(KOMP)Wtsi
Genetic
Background
C57BL/6N-Denrtm1b(KOMP)Wtsi/Wtsi
Cell Lines EPD0287_2_D07
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Denrtm1b(KOMP)Wtsi mutation (1 available); any Denr mutation (28 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
embryo
• small or absent trophoblast compartment
• biased differentiation (diploid/polyploid trophoblast)
• abnormal trophoblast giant cell size and morphology

mortality/aging




Genotype
MGI:5797474
ht2
Allelic
Composition
Denrtm1b(KOMP)Wtsi/Denr+
Genetic
Background
C57BL/6N-Denrtm1b(KOMP)Wtsi/Wtsi
Cell Lines EPD0287_2_D07
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Denrtm1b(KOMP)Wtsi mutation (1 available); any Denr mutation (28 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological

homeostasis/metabolism





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory