Phenotypes associated with this allele

• Allele Symbol: Gdf11^{tm2b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 2b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5636965
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gdf11^tm2b(EUCOMM)Hmgu/Gdf11^tm2b(EUCOMM)Hmgu	C57BL/6N-Gdf11^tm2b(EUCOMM)Hmgu/Bay	MGI:6262514
ht2	Gdf11^tm2b(EUCOMM)Hmgu/Gdf11^+	C57BL/6N-Gdf11^tm2b(EUCOMM)Hmgu/Bay	MGI:6461289

Genotype
MGI:6262514

hm1

• Allelic Composition: Gdf11^{tm2b(EUCOMM)Hmgu}/Gdf11^{tm2b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Gdf11^{tm2b(EUCOMM)Hmgu}/Bay
• Cell Lines: HEPD0802_3_E05

Data Sources

IMPC Data for Gdf11

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal craniofacial morphology ( J:211773 )

♀

IMPC - BCM

abnormal facial morphology ( J:211773 )

♀

IMPC - BCM

cleft palate ( J:211773 )

IMPC - BCM

digestive/alimentary system

cleft palate ( J:211773 )

IMPC - BCM

growth/size/body

abnormal facial morphology ( J:211773 )

♀

IMPC - BCM

cleft palate ( J:211773 )

IMPC - BCM

limbs/digits/tail

abnormal tail morphology ( J:211773 )

IMPC - BCM

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - BCM

Genotype
MGI:6461289

ht2

• Allelic Composition: Gdf11^{tm2b(EUCOMM)Hmgu}/Gdf11⁺
• Genetic Background: C57BL/6N-Gdf11^{tm2b(EUCOMM)Hmgu}/Bay
• Cell Lines: HEPD0802_3_E05

Data Sources

IMPC Data for Gdf11

cardiovascular system

increased cardiac stroke volume ( J:211773 )

♀

IMPC - BCM